Discover and read the best of Twitter Threads about #AtrialFibrillation

Most recents (14)

💥#McMaster #CardiologyGrandRounds by @johneikelboom
🩸 People with #AF are inadequately anticoagulated, largely related to MD hesitancy
🩸#Bleeding risk prediction tools have modest performance
🩸Bleeding risk iproportional to stroke risk, net benefit favours #antocoagulation
2/
🩸Few reasons to withhold #OAC, even in frail, older adults
🩸Across spectrum of #bleeding risk in AF, #stroke risk is higher
🩸#DOACs preferred over warfarin in #nonvalvular #AF
3/
🩸Most #DOACs safe in #CKD, some require dose adjustment
🩸Dabigatran contraindicated in eGFR<30
🩸Limited RCT evidence in #Hemodialysis

#AtrialFibrillation #Anticoagulation
Read 4 tweets
Really pleased to share the results of the #LongCovid study I was part of with the Perspectum team out of Oxford University. Using a specialist new technology this focused on assessing multiple organ damage in 'first wave' patients, infected with #COVID in early 2020 or even 2019
We were given in-depth haemotological tests, respiratory assessments and most importantly whole organ scans using the new 'MRI' type enhanced scanning equipment. My first test showed #myocarditis, three liver #lesions, reduced #kidney function and multiple organ inflammation
Also in the first year I experienced #TIA, #atrialfibrillation, #septic bursitis, pre-diabetic symptoms, complete loss of taste & smell; hair loss; #polyarthritis joints, abdominal and bone pain plus multiple #infections and skin eruptions Some neuralgia, headaches and brain fog
Read 5 tweets
1a) Welcome to a new #accredited #tweetorial, “MOA and Clinical Trial Data for Novel & Emerging Therapeutic Strategies for #HCM: Can We Target Our Therapy?"
1b) Our expert (and returning @cardiomet_ce) author is Giuseppe Galati MD, MMSc in Heart Failure, FHFA, @GiuseppeGalati_ , Consultant #Cardiologist #HeartFailure & #Cardiomyopathies
2) @GiuseppeGalati_ is in Milan 🇮🇹 This program is intended for #healthcare professionals & is accredited for 0.75h CE/#CME credit for #physicians #physicianassistants #nurses #nursepractitioners #pharmacists.
Read 46 tweets
Is sex a critical factor for treating #AtrialFibrillation?❤️‍🩹

New #CardiovascularResearch study examines #SexDifferences in calcium handling & therapies in patients with #AFib
academic.oup.com/cardiovascres/…

Our tweetorial explains the findings⬇️👩‍🏫

@ESC_Journals @escardio #EPeeps (1/9)
#Atrial #myocytes were isolated from patients with & without #AtrialFibrillation

Sex differences in #risk factors & therapies were considered in the analysis (2/9)
To explore #SexDifferences in the mechanisms of #Afib, calcium handling was examined & calcium handling proteins investigated (3/9)
Read 9 tweets
1) Welcome to an #accredited #tweetorial on a unique emerging (in Ph3 now) option for specifically reversing the #antiplatelet effects of #ticagrelor: it's #bentracimab. Expert faculty is antithrombotic agent reversal guru @md_pollack of @UMMCnews, working to create #AHealthierMS
2) This program is intended for #healthcare professionals and is supported by an educational grant from PhaseBio Pharmaceuticals. Faculty disclosures are listed at cardiometabolic-ce.com/disclosures/, and prior programs are available for 🆓CE/#CME credit at cardiometabolic-ce.com.
3) It is an unfortunate fact of life that one cannot prescribe #anticoagulant or #antiplatelet (together, #antithrombotic) therapy without increasing a patient's #bleedingrisk. That is why it should be an individualized risk:benefit decision, ideally . . .
Read 51 tweets
1) Welcome to a new joint-accredited #tweetorial on the highlights of cutting-edge #cardiometabolic research from this years #ESCCongress. We are
@GoggleDocs. Follow this tweetorial to earn FREE 0.75h credit, #physicians #nurses #pharmacists!
@MedTweetorials
#FOAMed #medtwitter
2) This program is intended for healthcare professionals and is supported by educational grants from AstraZeneca, Bayer, Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company, Chiesi, and NovoNordisk. See archived programs at cardiometabolic-ce.com.
3) Over the next 3 days the @GoggleDocs will be #Takeover with @cardiomet_CE account.

We are four 🇬🇧 based doc working across healthcare.

Our interests are "what's new, and meaning full in cardio-renal metabolic medicine"

Check out our YouTube channel youtube.com/c/GoggleDocs
Read 16 tweets
Today @JAMACardio published our study on potential risk/benefit of anticoagulation for #AFib pts aged 65-74 yrs w/out other CHADS2Vasc risk factors. This is one of the greatest areas of divergence of @SCC_CCS guidelines from @ACCinTouch @escardio
jamanetwork.com/journals/jamac…
This study was prompted by a patient with #afib who challenged me to justify my recommendation to anticoagulate her on her 65th birthday for rest of her life. She asked what her risk of stroke is if she chose not to anticoagulate & if it outweighs bleeding risk.
When stroke risk exceeds 0.9% per year, people with #atrialfib likely benefit from newer and safer bloodthinners (DOACs) but are unlikely to benefit from the older cheaper bloodthinner known as warfarin unless their stroke risk exceeds 1.7% per year.
ahajournals.org/doi/10.1161/CI…
Read 11 tweets
This cluster randomised controlled trial found that opportunistic screening in primary care did not increase the detection of #AFib compared with usual care in patients aged 65 & over @bmj_latest bmj.com/content/370/bm…
Image
Yet the findings are in contrast to the SAFE study which showed that opportunistic screening for #atrialfibrillation over a year detected more new diagnoses than usual care.
Read 8 tweets
‘ ... it is unlikely that #caffeine [#coffee, #tea] consumption causes or contributes to #AtrialFibrillation. Habitual caffeine consumption might be associated with lower risk of #AFib, but caffeine intake may increase symptoms of #palpitations unrelated to #AF.’
2020 ESC Guidelines for the diagnosis and management of #AtrialFibrillation #ESCCongress : academic.oup.com/eurheartj/adva…
☕️
Read 3 tweets
‘Overall, #antiplatelet monotherapy is ineffective for #stroke prevention [for #AtrialFibrillation] & potentially harmful (especially #elderly), whereas #DAPT associated with bleeding risk similar to OAC. Hence, antiplatelets should not be used for #stroke prevention in #AF
2020 ESC Guidelines for the diagnosis and management of #AtrialFibrillation #ESCCongress : academic.oup.com/eurheartj/adva…
‘Between 2009 & 2018, in #England, the use of #OAC for #stroke prophylaxis in #AtrialFibrillation increased, with #DOAC accounting for over half of OAC uptake in 2018.’
Read 7 tweets
‘4.1 Prediction of incident #AtrialFibrillation:
Identifying individuals at higher risk of developing #AFib in the community could facilitate targeting of preventive interventions & screening programmes for early #AF detection, for example in high-risk subgroups‘ #ESCCongress
... & this is what we will being investigating @UoLCardioEpi @UoL_LICAMM as part of our @TheBHF funded grant. Using #AI to predict incident #AFib from nationwide primary care #data; @JianhuaWu6
2020 ESC Guidelines for the diagnosis and management of #AtrialFibrillation : #ESCCongress academic.oup.com/eurheartj/adva…
Read 3 tweets
‘Very short episodes (≤10-20 s/day) of AHRE/subclinical #AFib are irrelevant, as not associated with longer episodes or increased risk of #stroke / systemic embolism. However, longer episodes (minimum 5-6 min) are associated with increased risk of #AF, ischaemic stroke & MACE’
2020 ESC Guidelines for the diagnosis and management of #AtrialFibrillation #ESCCongress : academic.oup.com/eurheartj/adva…
‘Notably, patients with subclinical #AF/AHRE may develop atrial tachyarrhythmias lasting more than 24 h or clinical #AFib; hence careful monitoring of these patients is recommended, even considering remote monitoring, especially with longer AHRE & higher risk profile.’
Read 6 tweets
For people >= 80 years of age with non-valvular #AF, once-daily #edoxaban 15mg was superior to placebo in preventing #stroke or systemic embolism & did not result in a higher incidence of major #bleeding than placebo
| #AFib #Elderly #NOAC 🇯🇵 @NEJM nejm.org/doi/full/10.10…
Participants were elderly Japanese patients (≥80 years of age) with nonvalvular #AtrialFibrillation who were not considered to be appropriate candidates for oral #anticoagulant therapy at doses approved for #stroke prevention.
Read 3 tweets
For #TransDayofRemembrance I want to tell you a story.

Last Nov/Dec, I was homeless. @realDonaldTrump had just been elected. I was living in my car. I was cold. I was hungry. The pain from my chronic lower back issues was horribly bad, every moment of every day (1/x)
Sleeping in my car was making it worse. I could barely stand, let alone go grocery shopping or walk longer than about 10 min, w/o being totally wiped out for the next day or 2. I was receiving no medical treatment for being #trans, for my #AtrialFibrillation or my back pain (2/x)
I was unemployed, had no degree, didn't pass, and I was severely depressed.

Only a few ppl know this, but I think it's time to talk about it. I almost died last December. I didn't have much $, but I was doing research on the best methods to kill myself that'd be effective (3/x)
Read 24 tweets

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