Discover and read the best of Twitter Threads about #pLACO

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In this #tweetorial, we'll walk through our approach to uncovering #acidbase disorders & our mnemonic #pLACO using this example:

pH 7.28, pCO2 30, pO2 75
Na 145, Cl 103, HCO3 18
Albumin 4 mg/dL

nephsim.com/acid-base/

Step 1: what does the "p" in pLACO stand for?
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#pLACO

The p is for pH, which tells us how acidic/basic a solution is.

Normal arterial blood pH is 7.4. Anything less than that is acidEMIC and anything greater is alkalEMIC.

In our example, the pH is 7.28. Thus, we have an acidemia.

nephsim.com/acid-base/
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#pLACO

Step 2: The "L" stands for ✅ labs (pCO2, HCO3).

In our example, the pCO2 is ⬇️ ( normal = 40 mm Hg). The bicarbonate is also ⬇️ (normal = 24 meq/L).

Acidemia and ⬇️bicarbonate suggest that the PRIMARY process is a metabolic acidosis.

nephsim.com/acid-base/
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