Discover and read the best of Twitter Threads about #BQ1

Most recents (13)

⚠️NEXT BIG ONE—CDC has royally screwed up—unreleased data shows #XBB15, a super variant, surged to 40% US (CDC unreported for weeks!) & now causing hospitalization surges in NY/NE.➡️XBB15–a new recombinant strain—is both more immune evasive & better at infecting than #BQ & XBB.🧵 ImageImage
2) Multiple models show #XBB15 is much worse in transmission R value and infection rate than previous variants — faster by LEAPS and BOUNDS. @JPWeiland did some the earliest models on #XBB15 watching data in NY. it has only grown worse nationwide. ImageImageImage
3) in fact, when @JPWeiland first modeled #XBB15 before Xmas, the data shows XBB15 was 108% faster than the previously king #BQ1 variant. But with more data, XBB15 has further accelerated to now being 120% faster! ImageImage
Read 27 tweets
REPEALED—The FDA has now withdrawn authorization of the last #COVID19 MAB drug bebtelovimab, citing it is not expected to neutralize the dominant BQ.1 & BQ.1.1 subvariants. This takes away the last COVID monoclonal antibody treatment. Losing the tools! fda.gov/drugs/drug-saf… Image
2) For treatment of COVID, this was the last MAB. While Evusheld is still authorized, it’s for pre-exposure prophylaxis (prevention) in limited people. But even then it has limited efficacy against the newer #BA5 Omicron variants.

reuters.com/business/healt…
3) Earlier in October, FDA already warned doctors prescribing @AstraZeneca's Evusheld to inform patients of

"increased risk for developing COVID-19 when exposed to variants of SARS-CoV-2 that are not neutralized" fda.gov/drugs/drug-saf… Image
Read 5 tweets
Bonjour Monsieur le ministre de la @Sante_Gouv @FrcsBraun et bonjour à toutes vos équipes, au ministère ou dans les établissements publics concernés.
Vous pourriez nous permettre d'éviter tous un EI majeur, celui de la contamination par le #sarscov2 en fréquentant des lieux de
1/
soins où le masque n'est plus obligatoire.
Nombre de personnes se sachant #vulnérables doivent renoncer à des soins puisqu'être la seule personne masquée dans un environnement mal ventilé / aéré fait courir des risques majeurs notamment aux patients immunodéprimés puisque face
2/
au variant désormais dominant #BQ1 et ses déclinaisons l'#Evusheld est en échec (poke @Renalooo notamment).
Les supposés #nonvulnérables, encouragés par la #compol du #vivreavec sous-tendu par l'aberrant #tinquièteitsmild se croient forts et n'ont pas peur de ce rhume.
3/
Read 7 tweets
BREAKING—Beijing officials are recommending all residents of Chaoyang (mega district of 4+ million) to stay home on Monday—do not go indoors publicly, and do not leave the area. #BF7 variant suspected. China had its first death from #COVID19 since May. 🧵reuters.com/world/china/be… twitter.com/i/web/status/1…
2) Beijing is also recommending wearing the public to wear masks in public. And they mentioned the “highly contagious” #BF7 variant of Omicron being a potential factor.

#BringBackMasks

news.ifeng.com/c/8L69jLZd8as

news.cctv.com/2022/11/20/ART…
3) crazy how @Twitter put a warning label on my original post about CCTV website even though the Reuters version has the exact same info. reuters.com/world/china/be…
Read 9 tweets
Aux 🇺🇸 comme en 🇨🇵 (nous étions en avance) les variants #BQ1 et #BQ11 du #SARSCoV2 sont #dominants.
Malheureusement les #anticorpsminoclonaux sont inefficaces avec eux.
Les #immunodéprimés sont plus que jamais soumis au bon vouloir des autres .
1/
Or en lien avec une #compol toujours pas à hauteur, la majorité des 🇨🇵 entend #vivrecommeavant quand les autorités disent #vivreavec & #recommandations.
Au-delà du fait que cet égoïsme prospère sur un fond de #validisme voire d'#eugénisme complètement décomplexé.
2/
La petite musique du "les facteurs de risques sont l'#âge, les pathologies #cardiovasculaires, le #diabète, les pathologies respiratoires chroniques dont #asthme sévère et #BPCO mais aussi #mucoviscidose, l'#immunodépression (#dialyse #cancers), #obésité induit en erreur car
3/
Read 21 tweets
1/5 - “Les caractéristiques de #BQ11 lui confèrent un avantage de croissance de plus de 60 % sur #BA5. Son échappement immunitaire a été établi en laboratoire sur des titres d’anticorps neutralisants, et on attend des données en vie réelle.”
leparisien.fr/societe/pic-de…
2/5 - “Une nouvelle vague portée par #BQ1 (englobant #BQ11) ces prochaines semaines est jugée probable par l’ECDC. Mais quand ? Impossible de le savoir, d’autant plus que les vacances de la Toussaint viennent opportunément ralentir le phénomène de diffusion du virus.”
3/5 - “Les températures très au-dessus des normales de saison depuis la mi-octobre ont aussi probablement favorisé l’aération des habitations et les interactions sociales à l’extérieur.”
Read 5 tweets
⚠️BREAKING—CDC now confirms my scoop that super evasive #BQ1 & #BQ11 variants (Typhon & Cerberus) have meteorically surged from *unlisted* 3 weeks ago, to 11% 2 weeks ago—to ⬆️now suddenly 27% today! This is a bad 10-day doubling time! 🇬🇧’s #BQ ~30% too🧵
covid.cdc.gov/covid-data-tra… ImageImage
2) Moreover, In New York and New Jersey (plus PR) region - #BQ variants now at a whopping 42.5%—confirming my scoop again. They have now displaced even their immediate ancestor #BA5. Clearly #BQ1 and #BQ11 sub-variants are dominating the race for this fall. I’m worried for fall. Image
3) Everything I’ve warned for the last 2 weeks about #BQ variants have been confirmed. I’ve been told by my source that CDC leadership has been flustered and shaken — trying to defend their lackadaisical variant tracking of #BQ variants — it’s quite a dereliction of diligence. 😢
Read 11 tweets
⚠️SCOOP—Just learned bad #COVID news from my source. The less bad news first:📌the most evasive #XBB recombination escape variant to date, albeit <1%, but no longer 0%. 📌Worse: very evasive #BQ variants now spiked to 27%—w/ 42% in NY/NJ where 🏥 surging. Doubling time—10 days!🧵
2) the data will be released by the CDC mid day tomorrow (Friday). The #BQ11 & #BQ1 variants were just 11% two weeks ago, and 16.6% last week. This week—27% nationwide!! That’s a huge surge. The 27% will be reported tomorrow. But this is a meteoric rise!
3) It has been conveyed to me that my scoop 2 weeks ago upset the @CDCgov leadership, who were caught trying to defend how they neglected to inform the public that #BQ variants went from UNLISTED to suddenly 11%. It was epically embarrassing of @CDCDirector.
Read 15 tweets
🎉CoVariants.org Update!🎉

22E (BQ.1*) is now available on CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.

1/8

#BQ1 #22E

covariants.org/variants/22E.O… Image
This is in line with the recent addition of 22E (BQ.1*) as a @nextstrain clade - read more on that below! 👇🏻

2/8

On the 22E page, you can read about some initial 22E / BQ.1 work on neutralizing titres, see a list of defining mutations, a plot of the variant growth, link to Aquaria protein viz, & see a list of other mutations present in the variant.

3/8

covariants.org/variants/22E.O… ImageImage
Read 8 tweets
#JustPublished!
Spread of the #SARSCoV2 #Omicron variant sub-lineage BQ.1 in the EU/EEA.

BQ.1, including its sub-lineages, has been designated as Variant of Interest (#VOI) by ECDC as of 20 October 2022.

Full report: bit.ly/3VMLay0 Image
Based on modelling estimates, it is expected that by mid-November to beginning of December 2022, more than 50% of #SARSCoV2 infections will be due to BQ.1/BQ.1.1.

That level is expected to rise by the beginning of 2023, to more than 80%.

bit.ly/3VMLay0
#Omicron #BQ1 Image
The observed increase in the growth rate of BQ.1 is probably driven mainly by immune escape.

This variant and its sub-lineages will probably contribute to a further increase in cases of #COVID19 in the EU/EEA in the coming weeks and months.

#Omicron #BQ1 Image
Read 7 tweets
1/5 - “#BQ11 est un sous-lignage #BQ1, lui-même sous-lignage de #BA5, lui-même sous-variant d’Omicron. […] La France semble faire la course en tête en Europe avec ce nouveau sous-variant #BQ11.”
actu.fr/societe/covid-…
2/5 - “#BQ11 pourrait bien venir contrecarrer la décrue épidémique qui s’amorce aujourd’hui avec le reflux de la 8e vague pandémique due au sous-variant #BA5 d’Omicron.”
3/5 - “#BQ11 représentait, mi-octobre, près de 40% des coronavirus séquencés, avec une augmentation très rapide : de quelques pourcents en septembre et de moins de 15% début octobre seulement. Il y a fort à parier qu’il sera dominant dans toute l’Europe avant la fin de l’année.”
Read 5 tweets
⚠️Scoop—MOTHER OF GOD—Just got this leak from CDC-insider source—it seems #COVID variants worse than CDC has been admitting. The new highly evasive #BQ1 & #BQ11 sub variants are surging over 11%—but CDC has not shared it yet! Here is what will be posted soon (left) 🆚 current. 🧵
2) I cannot describe just how mad I am at this disaster. #BQ1 and #BQ11 are two of the most evasive variants known to date. And CDC seems to have been holding onto this data? Can it be true? Why did this data have to leak to me from insider sources? It’s so bad.
3) So, HOW BAD IS IT??? People don’t get what I mean by among the “most evasive” — the #BQ1 (Typhon) and #BQ11 (Cerberus) are basically dubbed “escape variants” because they escape from immunity!! 👀

Nickname by @TRyanGregory
Graph by @RajlabN
public.tableau.com/app/profile/ra…
Read 10 tweets
新冠应该回归流感管理,这样中国人民就不用被到处核酸,封城、转运、隔离。因为其起源,病毒特点,甚至高峰时间,都可提前准确在社交媒体预警到。起始污染中心-野生动物市场, 中介-穿山甲,规模-全民受害。DELTA-暑湿,全球高峰-8月29。OMICRON-寒湿,全球高峰-1月20号。BA5子变体-暑湿,高峰8月底 /1 ImageImageImageImage
#新冠病毒 为适应 #极冷冬天 正在不断优化组合进行变异为超级耐寒的寒湿病毒,其免疫逃逸功能可能能逃过所有疫苗和感染形成的抗体,再如以前一样集体排队 #核酸检测 或许是加重疫情,极冷的室外进行核酸容易使人得风寒,导致人体抵抗寒湿病毒的免疫力下降。如移到在空气不通畅的室内则容易交叉传播 /2
#新冠 是季节性 #流感 的变异循环,每次大变异后的领跑者都能逃逸以前的疫苗或以前感染的抗体。今年马上要袭击人类 #寒湿 症变异毒株到来之前, 食用一些可明显提升阳气,暧身的天然食品比如生姜洋葱红茶加运动等提升免疫力辅助防备,足以免除核酸隔离转运,社会可恢复正常 。
Read 42 tweets

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