Discover and read the best of Twitter Threads about #Legionella

Most recents (4)

"Mysterious outbreak in Argentina solved"

Newly interested in #Legionella? Here's an excerpt from my book, #HealthyBuildings (in the opening chapter, after my FBI story...)

And...good time to mention...new edition comes out October 18. First look at the new cover!

1/n
It was during one of my first forensic investigations of a “sick building” that I first saw the power and potential of this burgeoning Healthy Buildings movement. This was no ordinary case of sick building syndrome...
It wasn’t a stuffy cubicle farm where people sometimes report symptoms like headaches, eye irritation, dizziness, or allergic reactions. I don’t mean to diminish those types of sick buildings in any way, but this was a hospital and the lives of four people were in jeopardy.
Read 25 tweets
#idboardreview 20 F w/ SLE on hydroxychloroquine & recently high dose steroids for SLE flare presents w/F, dyspnea, diarrhea, wbc6k, Na133, COVID/RVPneg, procal9, galactomann neg, dx? #meded #idmeded #idtwitter ImageImage
#Legionella cavitary pneumonia is atypical presentation of Legionnaire’s disease & more commonly w/ impaired cellular immunity due to corticosteroids (particularly high-dose steroid), immunosuppressive therapy, organ transplant & HIV infection; Case Ref idimages
Cavitation seen w/ #Legionella pneumophila serotypes 1,3,4,5,6,8 as well as L. micdadei, L. bozemanae, L. dumoffii, L. longbeachae.
L. pneumophila 1 is main agent of Legionnaire’s disease. Non-serotype 1 & non-pneumophila Legionella occur in severely immunocompromised hosts
Read 5 tweets
Weekend Digest

Name the pathogen and its treatment.

Clues:
1. Grows within protozoa
2. Decorative fountains
3. Hotel stay during travel
4. Cough + diarrhea
5. Antigen test
2/
#Legionella species

Aerobic “intracellular” GNB
>60 species

L. #pneumophila serogroup 1 - most common cause of human illness (water exposure)

L. #longbeachae (ANZ / soil, potting mix and compost exposure)
3/
#Legionella #pneumophila

Lakes. Streams. Reservoirs.

In water:
1. Planktonic
2. Biofilms
3. Intracellular in protozoa / free-living amoeba (protects bacteria from disinfection)
Read 9 tweets
#idboardreview 50 M from Australia works at wastewater treatment facility presents w/ fever, cough, dyspnea wbc10k, Na130, Tbili7, Alk270, AST75,ALT110 , LLL consolidation. diagnosis? #meded #idmedEd #idtwitter
#Legionella #longbeachae far less common species in US despite its discovery in Long Beach, California (<5% of legionellosis). L #longbeachae is endemic in Australia & New Zealand
#Legionnaires disease: CAP but more GI sx (N, V, D, abd pain), neurological sx (HA, seizure, FND, obtundation) & labs (low sodium/phosphorus, inc CPK, inc LFTs, inc inflammatory markers, myoglobinurea, microscopic hematuria & relative lymphopenia)
Read 12 tweets

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