Discover and read the best of Twitter Threads about #Neuropeptide

Most recents (2)

Excited to share our new manuscript on a novel #neuropeptide family that regulates #feeding across #evolution. Kudos to @Pat_TFrancisco for tackling this challenging project and coming up with the name @marmite . #homeostasis biorxiv.org/content/10.110… 1/22
Also kudos to all our collaborators @TastekinIbrahim @EzraGili @fern1_ana @BartDeplancke @albinojorgemai @alisson_gontijo which allowed us to expand the scope of our study and contributed critical insights. It takes a village 2/22
The sequencing of #genomes has been a major milestone in #biology. We have precise maps of the #genome of animals and we think that we know all the major players. Especially the conserved ones which are so important that most animals have them. But is it really like that? 3/22
Read 22 tweets
1/4 A toolkit of new GRAB fluorescent neuropeptide sensors from Li Lab! These sensors can detect neuropeptides at nanomolar concentration with a robust increase in fluorescence. #GRABSensors #Neuropeptide
2/4 GRAB-CRF1.0 reveals in vivo CRF dynamics in the cortex and hypothalamus induced by stressful experiences using fiber photometry and 2-photon imaging in mice.
3/4 We used these GRAB neuropeptide sensors to measure the spatiotemporal dynamics of endogenous SST release in isolated pancreatic islets and to detect the release of both CCK and CRF in acute brain slices.
Read 5 tweets

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