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Hey #Medtwitter & #Neurotwitter With 2 simple rules you can learn the #basalganglia direct and indirect pathways for the LAST TIME and actually remember them! 🤯Here’s how! 🧵 :
#MedEd #medicalstudent #Neurology #Neurologyresident #Movementdisorders #Neuroscience #Neuroanatomy
Rule 1: The “OG” basal ganglia (striatum and globus pallidi) use GABA ➖as their neurotransmitter. Everything else uses glutamate ➕.

Rule 2: Once you know Rule 1, all you have to do is memorize the order of the structures:

Direct pathway: CS___GiT
Indirect pathway: CS GeS GiT
Both pathways start with
cortex (C)>striatum (S)
and end with globus pallidus internus (Gi)>Thalamus (T).

For the indirect, just add GeS (Globus pallidus externus>STN) in the middle!
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