1/9 Some people do not want to change or be told they are not eating the right foods. A powerful reason is not only their addiction to these detrimental foods but also their attachment to the medical community which gives them unsubstantial /2

https://twitter.com/Mangan150/status/1785374543063765381

2/9 nutritional information, and because the medical establishment has become so revered over decades, they are the last word. Obesity isn't a disease. It's a lifestyle affliction, a side-effect of poor dietary choices & conflicted dietary advice from the Govt & Food industry. /3

1/8 Mevalonate is the essence of cell renewal. In all cells Mevalonate travels down the Mevalonate pathway to make cholesterol and Isoprenoids (five-carbon molecules). Both stimulate the cell to grow, replicate its DNA and divide into two cells. /2

https://twitter.com/ClausCarlsen1/status/1785291926360539223

2/8 This is the ‘cell cycle. This is LIFE. The Mevalonate blockade of Statin drugs is what kills cells, so it goes without saying that EVERY cell in your body will be affected. These are not Statin “side effects” these are the “direct effects” of ingesting a Statin drug. /3

1/9 While food and nutrition are very important influences on Atherosclerosis, there is also mounting evidence that infectious pathogens may initiate Atherosclerosis suggesting that microorganisms may play a causal role. A clue is the fact that lipoproteins constitute
/2 2/9 an innate immune system by binding and inactivating microorganisms and their toxic products through formation of circulating complexes. Their particle size may change in the presence of hyper-homocysteinemia because homocysteine reacts with LDL cholesterol to form
/3

1/10 Chronic inflammatory diseases, such as rheumatoid arthritis, lupus, psoriasis, & infections such as periodontal disease (p.gingivalis), & HIV, are associated with an increased risk of heart disease. Patients with these disorders also have an increase in coronary artery /2 2/10 calcium measured by CT & carotid intima media thickness measured by ultrasound. WHY ?? Because inflammation & infections induce a variety of alterations in lipid metabolism that may initially DAMPEN inflammation or fight infection, but if chronic, can contribute to the /3

1/4 Bile acids are important metabolic regulators. Statins inhibit the production of cholesterol, the precursor of bile acids. Their use significantly depletes the bile acid pool, particularly when enterohepatic circulation of bile acids is disturbed
/2 2/4 Bile acids control gut bacteria overgrowth, species population, and protect the integrity of the intestinal barrier.
Gut bacteria, in turn, control circulating bile acid composition and pool size. /3

1/6 MITOCHONDRIA - THEY ARE THE FORCE Mitochondria evolved to be the powerhouses, or energy factories, of the cell. They are organelles that act like a cellular digestive system that takes in nutrients, breaks them down, and creates ENERGY for the cell. /2

1/5 Statins are mitochondrial toxins. There are many ways in which Statin increase coronary artery calcification. Sufficient production of vital biochemicals such as Geranylgeraniol (GGPP) is required to maintain endotoxin tolerance in macrophages.
/2 2/5 Macrophages are the hallmarks of CVD/Atherosclerosis, contributing to plaque development, inflammation, and the promotion of thrombosis. Geranylgeraniol is downstream of Mevalonate in the cholesterol synthesis pathway,
/3

1/4 The theory that Cholesterol ‘clogs arteries’, causing heart attacks & stroke is an illusion that does not stand up to any physiological, experimental, epidemiological or clinical argument.
Contrary to current dogma, Statins do not prevent heart disease or reduce mortality /2 2/4 Statins are Mycotoxins and taking Statins can lead to diabetes, cancer, muscle damage, cognitive impairment, sexual dysfunction, heart failure, stroke, and serious autoimmunie disease such as Parkinson’s, ALS, Rheumatoid Arthritis and Lupus to name but a few.
/3

1/5 Are pharmaceutical companies aware that Mycotoxins (Statins) can cause cancer ? Of course they are. Do they tell the FDA or the MHRA that drugs, such as Statins are fungal toxins ? No, they don’t. Instead, they promote Statin drugs as “secondary fungal metabolites”. /2 2/5 Doctors don’t know what that means and neither do the regulatory authorities, or if they do, they're not letting on😉. It has been demonstrated that there is a connection between disruption of the Mevalonate Pathway by a Mycotoxin and an increase in Reductase and cancer. /3

1/8 Low Cholesterol leads to an early death Lymphocytes are a type of white blood cell which help to protect the body against disease & infection. T cells are a type of white blood cell that directs the immune system to defend against bacteria and other harmful pathogens. /2 2/8 CD8+ cells are T cells that release cytokines. Cytokines are substances that communicate to the immune system that there are “foreign harmful invaders": Prof Matthew Muldoon from the University of Pittsburg notes that low cholesterol levels in apparently healthy /3

1/7 This person - taking Atorvastatin (Lipitor) for 18 years has now been told he has “a kind of Motor Neurone Disease or Parkinson’s”. This is absolutely appalling since we know that Cholesterol is required to maintain the health of the myelin sheath that surrounds and /2

https://twitter.com/gmohan64/status/1781702505111662901

2/7 protects neurones. Glial cells in the brain, sustain the myelin sheath by synthesizing their own cholesterol and transferring it across to neurones, and suchlike.
Knowing how vital cholesterol is for the health of neurones, it is obvious that Statins can and do lead to /3

1/8 Prior to the introduction of Statin drugs in the late 1990’s there were a number of studies done in which cholesterol was successfully lowered by other drugs, notably Fibrates. These drugs actually lowered cholesterol quite well. If lowering cholesterol quite well does /2

https://twitter.com/DietHeartNews/status/1780970540255056079

2/8 in fact prevent heart disease or strokes, we should see a significant reduction in heart attacks and strokes anytime we successfully lower it, regardless of the particular drug or diet used to accomplish this.
(agreed ??)

Now get this: Investigations of the cholesterol
/3

1/5 LDL and HDL are the predominant Lipopolysaccharide binding proteins in patients with Sepsis, primarily through the interaction of LPS-binding protein with LDL and HDL. It is therefore not surprising that LDL receptor-deficient mice, with increased circulating LDL serum /2

https://twitter.com/DietHeartNews/status/1646550027483873284

2/5 levels are protected against the lethal effects of Endotoxemia and Gram-negative infections . These associations suggest a cyclic pattern in which low LDL levels lead to reduced LPS binding, which increases the risk of infection, leading to increased risk of Sepsis,
/3

1/5 Statins are Mycotoxins. The lactone ring of Statins mimics a portion of HMG-CoA which Reductase converts into Mevalonate. By confusing the Statin for HMG-CoA-Reductase’s normal active site, this site is inhibited by the Statin. This results in the toxic effects of /2

https://twitter.com/holmanm/status/1746473238702477548

2/5 Reductase blockade & Mevalonate DEPRIVATION. When Reductase is blocked, cells make more Reductase which upregulates LDL receptors. Cells are eventually overloaded with cholesterol (via receptors) but they remain deprived of Isoprenoids (biochemicals which are essential
/2

1/15 From 2008 onwards I’ve been talking to members of Statins forums. Here we are in 2024 and nothing much has changed. These people are still being seriously harmed by Statin drugs and incurious Cardiologists are still prescribing these cell toxins. /2 2/15 To Doctors and Cardiologists: “Nothing limits intelligence more than ignorance; nothing fosters ignorance more than one's own opinions; nothing strengthens opinions more than refusing to look at reality, and the reality is that Statin drugs are doing REAL HARM. /3

1/6 In 1960 just 1% of men and 2% of women in England were classed as obese compared to today’s 25.2+ % of men and 27.7 % of women.
At the end of the 1950s, the average man weighed 10.2 stone (65kg) and the average woman 8.7 stone (55kg).
/2 2/6 Today the average weights are 13.2 stone (83.6kg) for men and 11.1 stone (70.2kg) for women
In the 1950's Natural fats had not been denigrated in favour of low fat, and had not been replaced with seed oils.
/3

1/4 Statins can cause Rhabdomyolysis. A serious medical condition that can be fatal or result in permanent disability. Rhabdomyolysis occurs when damaged muscle tissue releases its proteins and electrolytes into the blood. These substances damage the HEART and KIDNEYS.
/2 2/4 It beggars belief that Statins are prescribed to Kidney Transplant patients.

“Statins seem to be generally well tolerated in kidney transplant recipients” ??? 😡
However, Statin use might be associated with a higher risk of post-transplant diabetes mellitus, cataract,
/3

1/4 Perish the thought, but if I was prescribed a Statin drug I would want to know exactly what the drug contained and the precise mechanism of action of the drug. Why are people so incurious ?. Their health is at stake. When Statins lower cholesterol,
/2

https://twitter.com/holmanm/status/1743583657623736399

2/4 where do you think the cholesterol goes ? Do you think it evaporates ? Blood cholesterol is lowered by using a Mycotoxin which inhibits Reductase. This upregulates LDL receptors and blood cholesterol is shoved into organ and muscle cells /3

1/4 @OneEyedFancy is correct. Statins are diabetogenic agents and cause pre-diabetes. As far as Ezetimibe is concerned this drug inhibits intestinal & biliary cholesterol absorption but shows no difference in Atherosclerotic burden as measured by cartoid intima thickness. /2

https://twitter.com/OneEyedFancy/status/1775696242166698467

2/4 However, Ezetimibe used in mono therapy causes elevations in Transaminases (3 times the upper limit of normal with alanine transaminase or aspartate transaminase) A sign of LIVER DAMAGE. Ezetimibe also alters the hepatic profile of fatty acid components by significantly /2

1/4 Statins are mitochondrial toxins. There are many ways in which Statins increase coronary artery calcification. Sufficient production of vital biochemicals such as Geranylgeraniol (GGPP) are required to maintain endotoxin tolerance in macrophages.
/2 2/4 Macrophages are the hallmarks of CVD/Atherosclerosis, contributing to plaque development, inflammation, and the promotion of thrombosis. Geranylgeraniol GGPP is downstream of Mevalonate in the cholesterol synthesis pathway,
and GGPP synthesis is inhibited by Statins, /3

1/8 WHAT THE LDL ??
Because the presence of coronary artery disease can be associated with the proportion of small dense LDL, we analyzed the effect of Statins on small dense LDL subfractions in persons without CAD. /2 2/8 Unexpectedly,🤣 in that analysis, the proportion of small, dense LDL was significantly HIGHER in patients who were treated with Statins. Moreover, there were no differences in CRP, plasma fibrinogen, HOMA–IR, body mass index, or metabolic syndrome between the Statin and /3