nature.com/articles/s4159โฆ 2) The study analyzed the relationship between particulate matter (PM10 and PM2.5) levels and hospital admissions for respiratory and non-respiratory diseases in major cities in South Korea from 2016-2020.
2) The study developed a numerical model to simulate the transmission of SARS-CoV-2 virus through droplets expelled during coughing and sneezing on the upper deck of a passenger ship.
medrxiv.org/content/10.110โฆ 2) This was a prospective multicenter cohort study that examined long-term outcomes up to 12 months in 303 survivors of critical COVID-19 illness who were treated in ICUs in Sweden between May 2020-May 2021.
medrxiv.org/content/10.110โฆ 2) The study aimed to understand the progression of long-COVID symptoms over time in a cohort of 403 patients from a Midwestern long-COVID clinic.
129 patients completed a follow-up survey on average 1.45 years after their initial COVID-19 diagnosis.
Follow-up of over 120,000 participants ๐ medrxiv.org/content/10.110โฆ 2) This was a large prospective cohort study from Norway that investigated the trajectories of cognitive and physical symptoms before, during, and after SARS-CoV-2 infection. Over 120,000 participants were followed for up to 22 months.
medrxiv.org/content/10.110โฆ 2) Neuroimaging techniques like FDG-PET scans have been used to study changes in the brain associated with COVID-19. These scans measure glucose metabolism as a marker of neuronal activity.
"๐๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ฐ๐ฒ ๐ฎ๐ป๐ฑ ๐ถ๐ป๐๐ฒ๐ฟ๐๐๐ฎ๐๐ฒ ๐๐ฝ๐ฟ๐ฒ๐ฎ๐ฑ ๐ผ๐ณ ๐ต๐ถ๐ด๐ต๐น๐ ๐ฝ๐ฎ๐๐ต๐ผ๐ด๐ฒ๐ป๐ถ๐ฐ ๐ฎ๐๐ถ๐ฎ๐ป ๐ถ๐ป๐ณ๐น๐๐ฒ๐ป๐๐ฎ ๐(๐5๐ก1) ๐ถ๐ป ๐ฑ๐ฎ๐ถ๐ฟ๐ ๐ฐ๐ฎ๐๐๐น๐ฒ"
H/t @SpyrosLytras biorxiv.org/content/10.110โฆ 2) Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4 viruses pose a pandemic threat as they can infect multiple species including humans. The viruses have been spreading globally among wild birds, poultry, and some mammals since 2022.
onlinelibrary.wiley.com/doi/10.1111/joโฆ
๐๐ฅ๐๐๐๐ฃ๐๐ฉ๐๐ ๐ง๐๐ฅ๐ง๐ค๐๐ง๐๐ข๐๐ฃ๐
It refers to the process of modifying the epigenome, which consists of chemical modifications to DNA and its associated proteins, without changing the underlying DNA sequence. It involves the erasure of epigenetic marks ...
bmcinfectdis.biomedcentral.com/articles/10.11โฆ 2) The case presents a 52-year-old woman co-infected with H5N1 avian influenza virus and SARS-CoV-2, which caused severe pneumonia.
Her symptoms started with fever and progressed to shortness of breath and low blood pressure. CT scans showed lung lesions and pleural effusion.
Amazing results !!! thelancet.com/journals/lanamโฆ 2) Cuba conducted a nationwide pediatric vaccination campaign in September 2021 using the heterologous SOBERANA-02-Plus vaccine scheme (2 doses of SOBERANA-02 followed by 1 dose of SOBERANA-Plus). Over 95% of children aged 2-18 were fully vaccinated by December 2021.
๐๐ฏ๐ฆ ๐ฃ๐บ ๐ฐ๐ฏ๐ฆ ๐ค :
โถ๏ธ Toll-like receptors (TLRs) are a type of protein ... sciencedirect.com/science/articlโฆ 2) ... that plays a crucial role in the immune system. They are located on the surface of immune cells and are responsible for recognizing specific molecules from pathogens, as bacteria, viruses, and fungi. When TLRs detect these molecules ...
๐๐ฐ๐ณ ๐ต๐ฉ๐ฐ๐ด๐ฆ ๐ธ๐ฉ๐ฐ ๐ต๐ฉ๐ช๐ฏ๐ฌ ๐๐๐๐-๐๐๐-2 ๐ช๐ด ๐ซ๐ถ๐ด๐ต ๐ข ๐ต๐ช๐ฏ๐บ ๐ท๐ช๐ณ๐ถ๐ด ... ๐ cell.com/heliyon/fullteโฆ 2) The study aims to examine the protein-protein interaction (PPI) network between SARS-CoV-2 viral proteins and human host proteins. This can provide insights into potential therapeutic targets and drug repurposing opportunities for COVID-19
๐๐ฉ๐ข๐ฏ๐ฌ๐ด ๐ต๐ฐ ๐ฎ๐บ ๐ง๐ณ๐ช๐ฆ๐ฏ๐ฅ ๐๐ข๐ท๐ช๐ฅ @DavidJoffe64 pedneur.com/article/S0887-โฆ 2) The study analyzed 17 pediatric patients in Korea who experienced severe neurological manifestations associated with SARS-CoV-2 infection during the Omicron variant-predominant period from January to April 2022.
tandfonline.com/doi/full/10.10โฆ 2) The study assessed the kinetics of antibodies against SARS-CoV-2 among 137 employees of the Pasteur Institute of Tunis who had confirmed COVID-19 infection between September 2020-March 2021.
May 3 โข 5 tweets โข 2 min read
๐๐๐ฎ ๐จ๐ฉ๐ช๐๐ฎ :
"๐๐ค๐จ๐ฉ-๐พ๐ค๐ซ๐๐-19 ๐๐ค๐ฃ๐๐๐ฉ๐๐ค๐ฃ (๐๐ค๐ฃ๐ ๐พ๐ค๐ซ๐๐) ๐๐ฃ ๐๐๐๐ก๐๐ง๐๐ฃ ๐๐ฃ๐ ๐ฎ๐ค๐ช๐ฃ๐ ๐ฅ๐๐ค๐ฅ๐ก๐ 12 ๐ข๐ค๐ฃ๐ฉ๐๐จ ๐๐๐ฉ๐๐ง ๐๐ฃ๐๐๐๐ฉ๐๐ค๐ฃ ๐ค๐ง ๐ง๐๐๐ฃ๐๐๐๐ฉ๐๐ค๐ฃ ๐ฌ๐๐ฉ๐ ๐๐ข๐๐๐ง๐ค๐ฃ"
. nature.com/articles/s4159โฆ 2) This study aims to investigate the impact of the Omicron variant on young people 12 months after infection. The study included 345 young people who had their first laboratory-confirmed infection with the Omicron variant and 360 young people who were reinfected ...
โถ๏ธ Is the TRANSMISSION of the virus AIRBORNE or by DROPLETS ?
BOTH, even, if it is essentially airborne, due to the constraints of droplet transmission.
โถ๏ธ Is there a "relative" IMMUNITY ... 2) ... post-infection or post-vaccination ?
BOTH, even if reinfections must absolutely be avoided, and if the concept of hybrid immunity is dead, since there are almost no more vaccines administered
โถ๏ธ Is a WAVE caused by a VARIANT or by WANING IMMUNITY?
BOTH plus ...
We must first return to the objective of this study, because we cannot make accusations of intention to scientists, ... 2) ...when this ๐ผ๐ฏ๐ท๐ฒ๐ฐ๐๐ถ๐๐ฒ is clearly defined :
โถ๏ธ Determine the effects of a pre-alpha SARS-CoV-2 virus, to measure if there is aย protective immunity, induced by homologous vaccination and homologous or heterologous infection .ย
They could have done it with a recent ..
May 2 โข 7 tweets โข 2 min read
๐ผ "๐๐๐๐๐๐๐๐ ๐๐๐๐๐๐๐, ๐๐๐๐ผ๐๐๐๐๐๐, ๐๐๐๐ผ๐๐๐๐๐๐๐๐๐, ๐๐๐ผ๐๐๐๐, ๐๐ฃ๐ ๐ผ๐พ๐พ๐๐๐๐๐๐๐๐๐๐๐ " ๐๐ฅ๐ฅ๐ง๐ค๐๐๐ ๐ฉ๐ค ๐ข๐๐ฃ๐๐๐ ๐ฉ๐๐ ๐พ๐๐๐๐ฟ-19-๐ง๐๐ก๐๐ฉ๐๐ ๐ข๐๐ฃ๐ฉ๐๐ก ๐๐๐๐ก๐ฉ๐ ๐ฅ๐ง๐ค๐๐ก๐๐ข๐จ๐ค jstage.jst.go.jp/article/ghm/adโฆ 2) In psychology, the PERMA model is a well-known concept introduced by positive psychologist Martin Seligman.
This model suggests that by cultivating these elements in our lives, we can enhance our overall well-being and lead happier and more fulfilling lives.
nature.com/articles/s4146โฆ 2) The study characterizes the transmission dynamics of H9N2 avian influenza viruses (AIVs) in a live bird market (LBM) in Bangladesh.
Field data on AIV positivity from a controlled experiment involving broiler chickens and backyard chickens in an LBM was fitted to the model.
sciencedirect.com/science/articlโฆ 2) The study establishes a multi-age group
model to analyze the large COVID-19 outbreak in Fuzhou, China from November 2022 to February 2023.
The population is divided into 4 age groups based on surveillance data. Parameter values like transmission rates and ...
SARS-CoV-2, can infect and damage liver cells. It binds to ACE2 receptors which are highly expressed on cholangiocytes (bile duct cells) and can cause direct liver injury. wjgnet.com/1948-5182/fullโฆ 2) The liver is also vulnerable to indirect injury from COVID-19 through cytokine storm, hypoxic hepatitis due to respiratory failure, drug-induced liver injury from medications used to treat COVID-19, and exacerbation of pre-existing liver diseases.