Discover and read the best of Twitter Threads about #Manuscript

Most recents (20)

📢 Our new #manuscript shows how zero-shot Generative AI can create de novo antibodies from scratch.

🏅Hundreds of antibodies are created zero-shot and validated in the wet-lab for the first time ever.

Paper: biorxiv.org/content/10.110…
Data: github.com/AbSciBio/unloc… Image
Our zero-shot generative AI framework. The model is programmed with a target antigen structure and a chosen antibody scaffold sequence.

Antibodies are then generated de novo.

Note: all proteins binding the target (or its homologs) were removed from the training set. Image
We validate generated antibodies experimentally in the wet-lab.

Our platform is extremely high throughput. We can test ~3 million unique AI-generated designs each week.

A cycle of [AI ➡️ lab ➡️ data] takes just 6 weeks. Image
Read 10 tweets
#draadje #staatsgeheimen

In 2018 sprak ik 2x live #rolodex veroordeelde Nico Langeveld op een terras. Hij zat toen in open #TBS in Almere. Inmiddels zit hij weer gesloten en is hij overgeplaatst naar de #Boerhaavekliniek.

Tijdens zijn open TBS liet Nico zich opnieuw in met
jonge #kinderen, verboden #wapenbezit en nog eea. Mede mogelijk gemaakt door, jawel, @ferdgrapperhaus.

Nico vertelde me oa dat hij aanwezig was bij de nooit opgeloste #moord op bokser André Brilleman. Brilleman deed ook #securitywerk voor oa Bruinsma maar ook voor #Demmink. Wat
Nico me vertelde is dat Brilleman zijn mond niet kon houden. Om die reden hebben ze zijn geslachtsdeel afgesneden en in zijn mond gepropt met tape eroverheen en hem daarna in het water gegooid.

Wat Nico me ook vertelde was dat Demmink wel degelijk betrokken was bij het
Read 12 tweets
1/🧵This is Nabia Abbott. She was a groundbreaking scholar of #Arabic manuscripts, the first woman to be a professor at @UChicago’s Oriental Institute, and once sent me on a wild goose chase spanning 3 continents. She deserves a lot more than one thread, but here's a start.
2/Nabīha ʿAbūd (نبيهة عبود), later known as Nabia Abbott, was born in 1897 to a Christian family in Mardin (then the Ottoman Empire, now modern Turkey). Her family moved around a lot, which led to her attending school in India and completing a BA degree in Lucknow in 1919.
3/In 1923, Abbott moved to the US and earned her MA at @BU_Tweets. From 1925 on she taught at Asbury College (in Kentucky) where she eventually became the head of the Department of History. In 1933, she began a PhD at the @Orientalinst in Chicago (ark.digitalcommonwealth.org/ark:/50959/z60…).
Read 19 tweets
Have you ever searched for "How to do a #LiteratureReview quickly/in 1 day/3 hours"?
And then spend the entire time getting lost in searching/ wallowing in tangential directions?

Here is a🧵on Quick #LitRev technique...

#AcWri #AcademicTwitter #PhDtips #phdlife #ScienceTwitter Image
From my fair share of struggle with literature reviews, I devised a technique that helped me do *quick* literature surveys, especially when I needed to
- write a #grant #proposal
- improve a half-written #manuscript
- learn a new method/theory

So, here you go...
1️⃣Collecting literature: Research Rabbit App

My go-to tool for literature discovery+visualize connection b/w them. (very essential for writing your LitRev, as you will need to draw connections between different works.) Image
Read 14 tweets
Daily Bookmarks to GAVNet 12/03/2021 greeneracresvaluenetwork.wordpress.com/2021/12/03/dai…
Monarch butterflies may be thriving after years of decline. Is it a comeback?

theguardian.com/us-news/2021/n…

#MonarchButterflies #PopulationIncrease #DataAnalysis
Ignorant and Afraid - by eugyppius - eugyppius: a plague chronicle

eugyppius.substack.com/p/ignorant-and…

#politicians #bureaucrats #propaganda #information #ignorance #fear
Read 11 tweets
The @librarycongress has a fantastic Civil War collection. In it includes three manuscript volumes that document daily life in Washington, D.C., by U.S. Patent Office examiner Horatio Nelson Taft (1806-1888).
There are 1240 digitized pages of this collection, and they're amazing to scroll through! Be patient- the images force you to brush up on your paleography skills! (Thank you to @librarycongress staff for transcribing them!)
The documents include a"report of President Lincoln's assassination based on accounts Taft received from friends and particularly his son, Charles Sabin Taft, a US Army surgeon who was in Ford's Theatre the night Lincoln was shot." (LOC)
Read 5 tweets
This is beautiful!
This little #manuscript seems to be written by a regular, non-professional, member of the Jewish community of Fustat, Egypt, about 1000 years ago.
They made a little shorthand manuscript of #Psalms, for their own personal use. Image
This person knew the Psalms pretty well, so could abbreviate most of the words by chopping off the last letter or two (which seems more impressive when you remember that #Hebrew words tend to be short: say, 2-6 letters in the main).
This little snippet is from Psalm 9: 17-18.

But here, the writer's knowledge of the book of Psalms has actually led them astray...

Do you see the line in the image with lots of dots over all the letters? Those are erasure dots: (s)he wants, in effect, to cross out that line.
Read 6 tweets
Hello all! @SJLahey here, again. Let’s dive right in…

Yesterday, in my introductory overview thread, I opened with a teaser image showing a rather odd-looking piece of #parchment: part of an offcut.


But what does that mean? What is an offcut? 🤔
[A preliminary note: The word ‘offcut’ (or ‘off-cut’) has other definitions than the one below, particularly in archaeology, but also in other fields. To keep things simple, I won’t go into them in these threads—but feel free to ask questions, either here or @SJLahey]
By way of technical definition, in #codicology, an offcut is ‘a piece of parchment originating as a remnant created by the second cuts’ (i.e., when the prepared plano sheet is squared up by pruning away lower-grade material from around its perimeter).
Read 21 tweets
I am humbled and privilleged to note that my #Research paper; "Sources of #Unemployment in #Lesotho" is now available and can be accessed via the People's Republic of #China's National #Science and #Technology #Library - #NSTL. I give thanks 😎 Image
So far this year, I have successfully published three #Research articles in #Macroeconomics & #Finance, with another two in press. I am currently hammering away at a handful of working papers which will most certainly find a home in reputable #Journals, come 2021 🙏🏽🙂 Image
Im currently internalising the very insightful reviewer comments on my latest #Research paper titled; "Investigating Determinants of Commercial Bank Spreads in #Lesotho", from the good folks over at the globally reputable #International #Journal of #Finance & #Economics #IJFE 😊 ImageImage
Read 52 tweets
#manuscripts MS King Abdul Aziz Library Riyadh 906 #IslamicPhilosophy Mawdih al-diraya Li-sharh bab al-hidaya of Ibn Abi Jumhur al-Ahsa’i (d. 909/1503) 1/ ImageImageImage
IAJ was a prolific author in theology #fiqh philosophy on the cusp of the #Safavid period and there is a Institute devoted to publishing his work based in al-Ahsa headed by Sayyid ‘Ali al-Musa 2/ ImageImage
His best known works are his massive al-Mujli a combination of insights from #Shii #kalam #Avicennism #IshraqiPhilosophy and the #Sufism of #IbnArabi 3/ ImageImage
Read 14 tweets
Madinat al-‘Ilm seems to have been an early #ShiiHadith encyclopaedia compiled by Ibn Babawayh al-Shaykh al-Saduq (d. 991) but which has not been extant since the later 16thC 1/
Recently a recovered text based on citations has been published mktba.net/library.php?id… 2/
The early #Shii bibliographies all mention the text and that it was voluminous and larger than Man la yahduruhu l-Faqih - 10 to 4 in ratio 3/
Read 7 tweets
#manuscript #IslamicateMedicine an autograph of Muhammad Sharif Khatunabadi from the family of Bagir Majlisi on medical reports from the Prophet and Imams 1/ Image
MS Mar’ashi (Qum) 14597 dated 1111/1700 entitled Tuhfat al-abrar with paratext by the current librarian Sayyid Mahmud Mar’ashi 2/ Image
Andrew Newman (Edinburgh) has written on this genre of works and the rise of interest in the #Safavid period as part of the recovery of the #Shii heritage 3/
Read 5 tweets
This #SOASLangs week, we'll delve in our #African languages holdings @SOASLibrary and @SOAS_SpecColl, or rather just brush on their surface: with several 100s of languages and dialects represented, it is our most #multilingual collection!

#AfricanLanguages #Multilingualism ImageImageImage
Let's start with #Swahili also known as #Kiswahili.

This @SOAS "Language for Lockdown" video is a great introduction to the 1,200 years history of Swahili: .

#SOASLangs #SOASfromHome Image
@SOAS @CAS_SOAS @SOAS_SpecColl hold a great collection of Swahili manuscripts, see digital.soas.ac.uk/swahili.

Among them figure a few copies of al-Inkishafi "The Soul's Awakening", a 19th cent. poem by Sayyid Abdallah bin Ali bin Nassir.

#Swahili #SOASLangs #SOASfromHome #Inkishafi Image
Read 60 tweets
Today’s #SyriacPalimpsestsMonday I would like to devote to the oldest dated #Biblical #manuscript in existence. Those familiar with the field of #Syriac studies, might think in this respect of the manuscript held in the British Library, Add. 14425.
Indeed, this manuscript was copied by a scribe called Yoḥannan in 775 of the Seleucid era corresponding to 463/4 CE. The manuscript contains the Pentateuch and was produced not in #Edessa (the central hub of the early Syriac Christianity), but in Amid (today’s Diyarbakır).
This manuscript is often mentioned as the oldest dated Biblical manuscript in existence. One often tends to neglect another Syriac biblical manuscript, which is slightly older. It is also kept at the British Library, as Add. 14512.
Read 12 tweets
Now, starting 2nd thread in the series of "#Sanskrit and #SilkRoute".

• Topic - Discovery of Sanskrit on Silk Route.

(1/n)
2/n
Refer the map of #SilkRoute again. Do you see Takla Makan desert, North to Tibet ?

City of Kashgar at this desert separates the route in two parts - North & South.

See that Kucha town in the North route. Next tweets are related to Kucha. So, remember it.
3/n
It was 1890 CE. India was under the British rule.

Hamilton Bower is a British army officer. He is sent to Kucha (China) on a secret mission in search of a murderer.

He goes to Kucha and takes help of a local person to guide him. Local guide takes him to an old place.
Read 10 tweets
My mother taught us to ward off the Evil Eye by spitting. 💦

According to this #Syriac #manuscript (Or 6673) there are more hygienic ways of eliminating it, and a host of other ailments, misfortunes and generic evils. Let’s see what they are!

(Props to the Evangelists)

📿🧿
Let’s cut the gentle humour for... one tweet. This #manuscript was copied at the end of the 19th century by Church of the East believers in northern #Iraq. It’s part of a long tradition of prayer and medicine in the region, and it relies on a number of different belief systems.
Ok, first up is fear. St. George was not afraid when he slew the #dragon (also identified here as a Great #Monster), so why should you be? Offer him a prayer to allay distress and fears.

🐲🐉🙏
Read 17 tweets
Around 3000 BCE in eastern #Europe, a Proto-Balto-Slavic #language started to diverge from #ProtoIndoEuropean.

The #Slavic branch of the #IndoEuropean #languages began about 2,000 years later when Proto-Slavic deviated from Proto-Balto-Slavic.

[Image: commons.wikimedia.org/wiki/File:Balt…] Source: The Indo-European L...
As the #Slavic-speaking area expanded during the first millennium CE (striped area on map), Proto-Slavic transitioned to Common Slavic. The #language underwent minor changes that occurred mostly uniformly across eastern #Europe, thereby maintaining mutual intelligibility. A map of eastern Europe sho...
Around the year 1000 CE #CommonSlavic began to split into the South, West, and East branches to which all modern #Slavic #languages belong.

Roughly 315m people speak a Slavic #language, mostly in Eastern #Europe (including the #Balkan peninsula), #CentralAsia, and #Siberia. A map of Europe highlightin...
Read 359 tweets
I always liked personal journals as framing devices for Romantic or Gothic horror novels like in Dracula and Frankenstein. I decided to write a satirical thread using this same device but for a common #scientific #journey:
Personal Journal of Dr. Nicholas Gladman
-Day 1-
Our scientific voyage began this afternoon. I am excited for what we shall discover and observe. #Manuscript first draft almost complete. Weird dark clouds on the horizon but sure it is normal.
-Day 2-
Manuscript sent to co-authors for initial thoughts and edits. Am hopeful for quick turnover and minimal comments. Anderson died of freak roof collapse but I’m sure that doesn’t portend anything sinister.
Read 15 tweets
This semester we started a writing group in lab. We have to write:
4 Honors Thesis
1 MS Thesis
2 Comprehensive Exams (F31 style)
and papers and grants.

It seemed a little overwhelming at first, but we've broken it down. (1/n)
Step 1: We blocked out two hours every Monday to write together. #MadWriting
Step 2: We set bite-sized goals for every single writing project, due on Friday. (e.g., Feb1: draft methods and draft results headers), working back from everyone's individualized deadlines. (2/n)
For writing group, I bring snacks, and everyone gets coffee or tea, and we all sit together. In silence. Writing.

At the beginning of each writing group we all share what we plan to accomplish *in that session*, and then check in at the end of the two hours. (3/n)
Read 8 tweets
“My name is here presented more to be understood than to be read” said once a #Roman senator.
For my #EarlyMedievalPills, let’s explore what monograms can tell us about changes in political culture & social communication between late antiquity & #Carolingian times.
1/
Monogrammatic culture has its roots in the #classical world. Producers used monograms to mark mass-produced objects such as pottery. We also see them on Hellenistic coins. However, they didn’t encode the name of the issuing authority, but functioned as control marks.
2/
Influenced by Hellenistic models, #Roman emperors adopted monograms on their coins. They were used to encode the emperor’s name thus becoming personal graphic devices that could also mark certain objects the trade of which was an imperial monopoly.
3/
Read 30 tweets

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