Discover and read the best of Twitter Threads about #caffeine

In this one, both 3mg/kg and 6mg/kg doses of caffeine ingestion increased plasma catecholamine concentration and improved the average peak power output during a repeated sprint test in trained female team-sport players.

- Both doses of coffee ingestion improved the average peak power output attained by participants during the repeated sprint test compared to placebo, with no differences between doses.

- Peak and mean power output and the fatigue index did not improve during the individual sprints.

Read 4 tweets

This narrative review explores the mechanisms of action and efficacy of caffeine and the potential for combinations of caffeine and other dietary compounds to exert psychological effects in excess of those expected following caffeine alone.

Key Points:

- Caffeine, when taken alone, is associated with reasonably consistent ergogenic and psychological benefits. However, its effects on mental performance are limited, and do not encompass benefits to several sport-relevant cognitive domains.

Daniel Rosehill

@danielsrosehill

For fellow drinkers of #coldbrew #coffee: here are 2 v important charts from a food science journal showing how efficiently #caffeine is extracted. As I learned early on, it's deceptively easy to consume an unpleasant amount of #caffeine using this brewing method.

1. Caffeine concentration begins approaching steady state after about 400 minutes (6 2/3 hours). If you think that a 7 hour counter steep will avoid most of the caffeine ... this is wrong. You've extracted almost all of it at this point.

2. While cold water extracts caffeine less efficiently than hot brew methods, this is more than compensated for in cold brew by the much longer time the grinds are in contact with the water.

Read 7 tweets

Here, the consumption of caffeinated coffee was inversely associated with the risk of type 2 diabetes among US nurses with a history of gestational diabetes, with higher intakes being associated with a more favorable glucose metabolic profile among the type 2 diabetes-free women.

A few other notable findings:

- "This current study presents complementary findings on the inverse associations of coffee, particularly caffeinated coffee, with T2D progression for high-risk individuals with a history of GDM...

Read 9 tweets

This Mendelian randomization study finds coffee consumption to be causally associated with risk of oesophageal cancer, with some evidence that this is related to a temperature effect.

- Augmented risk of oesophageal cancer was the main determinant of the increased digestive system cancers with coffee drinking reported in the present study.

- Interestingly, thermal injury to the oesophagus may also be an important oncogenesis driving factor.

Read 7 tweets

Jorn Trommelen, PhD

@JornTrommelen

Does coffee cause dehydration?

A thread 🧵👇

#caffeine #coffee #hydration

It is often suggested that coffee causes dehydration. This is because coffee contains caffeine, which has a dehydrating effect. However, coffee also contains fluid which has a hydrating effect. Therefore, it can be questioned if coffee intake really causes dehydration.

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This study investigated the effect of coffee intake on hydration levels in habitual coffee consumers (3-6 cups a day). Each subject participated in two 3-day experiment periods: one coffee period and one water period.

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In this one, coffee was inversely associated with chronic kideny disease in a dose-dependent manner, particularly in females with the effect being stronger in those with higher SHBG and lower testosterone concentrations.

- Among more than 350,000 participants in the UK Biobank, coffee consumption reduced the risk of CKD regardless of genetic risk.

- The effect was sex-specific, and was modified by testosterone and SHBG.

Michael Gee ✝ 🇨🇦 🇺🇦 pinball!

Chief Pharmacist ✪

@ChiefPharmacst

𝐘𝐎𝐔𝐑 𝐌𝐄𝐃𝐈𝐂𝐀𝐓𝐈𝐎𝐍𝐒 & 𝐃𝐑𝐈𝐍𝐊𝐒

One of the most common questions patients ask me👇
Pharm, can I take my Medications with SOFT DRINKS ?

#ANSWER : It's NOT advisable to take your medications with Soft drinks UNLESS recommended by your Pharmacist.

LET ME EXPLAIN 👇

( 1.) Soft drinks are Carbonated water (carbonic #ACID + water).

- The ACID can render the drug "in or Less active" leading to sub-optimal clinical outcome.

- Soft drinks doesn't REALLY cause Ulcer but for can cause some ERODING effects on Ulcer patients & those with history

of Ulcer due to the Phosphoric acid & Carbonic acids present.

The ACID can also worsen the symptoms of Ulcer (such as bloating, stomach fullness, stomach irritation).

Taking Such Drinks with AntiUlcer medications can make such drugs abit less effective.

Read 10 tweets

@woodrailking

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Unknown deaths in Alberta and New Brunswick

But it's definitely not the clot shot they got

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#Alberta #NewBrunswick #Deaths #MysteriousDeaths #vaccine #BigPharma #CrimesAgainstHumanity #Meme

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Hotter nights increase the risk of death from heart disease for men in early 60s

It's definitely not the clot shot they got

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Lonely older women at greater risk of heart attack, study shows

It's definitely not the clot shot they got

.

Read 18 tweets

Jorn Trommelen, PhD

@JornTrommelen

Does caffeine improve exercise performance for everyone?

A thread 🧵👇

#caffeine #coffee #performance

Caffeine has shown to improve exercise performance. Therefore, caffeine is a popular supplement among athletes.

2/x

There appears to be much variation in the individual response to caffeine. This may be explained by variation in the CYP1A2 gene, which determines whether caffeine is metabolized fast or slow. Therefore, the effects of caffeine may depend on the activity of this gene.

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