Discover and read the best of Twitter Threads about #vascular

Most recents (11)

2/
Classically placed in the arm
May be placed in the leg (eg in #pediatrics /neonates – which may then terminate in the infrarenal IVC/iliacs)
.
#criticalcare #cardiovascular
3/
Advantages:
- Lower infection rate then central lines
- Used in the outpatient setting
- Can be used for several weeks to months
- Duration of PICC lines may be from 4 weeks to 6 months
(although they have been known to be functional for more than 300 days)
Read 20 tweets
Avec des vaccins à l'efficacité de plus en plus limitée (50% au mieux face à XBB 1.5 contre plus de 90% sur les premiers variants)
francais.medscape.com/voirarticle/36…

> face à l'échappement immunitaire, quelle logique de l'obligation vaccinale si d'ici l'été la protection tombe à 25/30% ?
On peut aussi noter le variant BQ.1.1 Cerberus...

À chaque mutation de + en + sélectionnée par la pression immunitaire et vaccinale, le virus mutant résistant est sélectionné et diminue l'efficacité vaccinale car la vitesse d'évolution et complexité du virus va + vite ImageImageImage
De + chaque réinfection ⬆️ les risques de décès, d'hospitalisation, mais aussi de + en + kde séquelles, notamment pulmonaires, troubles cardiovasculaires, hématologiques, diabétiques, gastro-intestinaux, rénaux, de santé mentale, musculo-squelettiques et neurologiques.
Read 14 tweets
There are positive effects of the #ketone body beta hydroxy-butyrate (BHB) on vascular function. Why? Very likely, the following things that we already know BHB does. And quite frankly, there are likely additional mechanisms that haven't even been discovered yet. 🧵(1/10)
BHB lowers high blood sugar, and that reduces the production of reactive oxygen species #ROS and #inflammation mediators. In other words, BHB reduces Oxidative Stress (2/10)
BHB increases endogenous #antioxidant production by upregulating gene expression in those pathways. So yes, #BHB reduces Oxidative Stress from that mechanism as well. (3/10)
Read 10 tweets
1) Welcome to a new #accredited #tweetorial, Update on New HFrEF Data from ESC 2022 with a Focus on Vericiguat. Our expert author is Giuseppe Galati MD, MMSc in Heart Failure, FHFA, @GiuseppeGalati_ , Consultant #Cardiologist #HeartFailure & #Cardiomyopathies
2) @GiuseppeGalati_ is at San Raffaele Research Hospital, Milan 🇮🇹 @SanRaffaeleMI. This program is intended for #healthcare professionals & is accredited for 0.75h CE/#CME credit for #physicians #physicianassistants #nurses #nursepractitioners #pharmacists.
3) This program is supported by an educational grant from Bayer. See archived programs still open for credit at cardiometabolic-ce.com. Statement of accreditation & faculty disclosures at cardiometabolic-ce.com/disclosures/.🙏 FOLLOW US !
Read 43 tweets
1) Welcome to a new #accredited #tweetorial on a🗝️ topic in #cancer care & #vascular medicine: #VTE (#DVT and #PE). Cancer patients are at⬆️risk from their disease, their comorbidities, & often from their treatment. It's a sticky wicket & @cardiomet_CE is proud to welcome ...
2) ... one of the world's leading authorities on cancer-associated VTE as new faculty both here and on @onc_ce: Dr. Alok Khorana @aakonc of @ClevelandClinic, to talk about advances and best treatment in this space!
3) This educational program is intended for health care providers & is supported by a grant from Bristol Myers Squibb & its Alliance partner Pfizer, Inc. Faculty disclosures are listed at cardiometabolic-ce.com/disclosures/. Earn CE/#CME credit from prior programs at cardiometabolic-ce.com.
Read 39 tweets
In silico identification of natural products from Centella asiatica as SARS-COV-2 main protease (M pro) inhibitor. 1/n

❌❌❌ #ritonavir #molnupiravir in #COVID19
No more #tryglyceride #mutagenesis

pubmed.ncbi.nlm.nih.gov/34345605/
2/n
Anti-Inflammatory and anti-vascular leakage effects by combination of Centella asiatica and Vitis vinifera L. (Grapevine) leaf extracts.
#antiinflammatory qualities #anti #vascular #leakage effect

hindawi.com/journals/ecam/…
Read 8 tweets
3/ Clot is in a constant state of evolution. #Fibrin—> #Collagen.
 
Unfortunately many patients present in the subacute or late phase of #clot development which hinders many of our treatment approaches.
 
7️⃣days- 20% collagen

1️⃣5️⃣ days- 50% collagen

2️⃣1️⃣days- 80% (!!) collagen
Read 39 tweets
#WeekendLecture
#PregnancyAndStroke

#Pregnancy and #puerperium confer an ⬆️ risk for ischemic as well as hemorrhagic stroke, with incidence rates being 3-fold higher as compared with nonpregnant women

👉doi.org/10.1016/j.ncl.…

a short 🧵 Image
#WeekendLecture
#PregnancyAndStroke

@DrRickSwartz @patrice_lindsay et al metaanalysis
👉11 studies
👉>85 million #pregnancy and #postpartum admissions in various countries
👉overall incidence of #stroke was 30 per 100,000 hospitalizations👈
@IntJStroke

journals.sagepub.com/doi/10.1177/17… ImageImage
#WeekendLecture
#PregnancyAndStroke
RFs:
☑️Age, >40yo OR3.1
☑️Race/ethnicity
☑️Migraine, thrombophilia, SLE, 🫀disease, HTN, thrombocytopenia, diabetes
☑️Pregnancy complications
✅For hemorrhagic stroke: aneurysms, AVM, Hypertensive Disorders of Pregnancy

journals.lww.com/greenjournal/F… ImageImage
Read 12 tweets
1/ Welcome to the first part of a #Tweetorial series on #VenousDisease.

🩸To begin how about we talk about the main player in the game- C.L.O.T. (and why you should care about it)

#Cardiotwitter #Irad #fellows #fellowtwitter #medthread #clot #medtwitter #clottwitter
3/ All clots ARE NOT born equally! There is a difference! Image
Read 34 tweets
1/ NAME THAT #COMPRESSIONSYNDROME

Patient with left flank pain, pelvic pain, hematuria and gonadal varices

Your only imaging modality is vascular U/S....Lets find out!

A Mohan #Tweetorial

#RPVI #cardiotwitter #irad #vascular @HadyLichaaMD @t_intheleadcoat @TheNarulaSeries
2/ What’s going on here?? First name your structures #RPVI

SMA- superior mesenteric artery
AO- Descending Aorta
Lt renal VN- left renal vein

@CHICKVIR @Jonathan_PaulMD @iRadRock @keithppereira @Vascupedia_com @DrYanLiu
3/ Save this- transverse slice at the level of the renals! So much anatomy in such a confined space

#RPVI #cardiotwitter #IRAD #Vascular #foamed #cardioed #cardiology #ultrasound #pocus
Read 11 tweets
Endothelial-derived microvesicles play a pathogenic role in vascular #inflammation, causing #endothelial barrier dysfunction by impairing adherens junctions and activating #neutrophils

More here: bit.ly/3g1FpH7
#Cardiotwitter #CardiovascularResearch

#Tweetorial below! Image
#Microvesicles (MV) are formed from the outward blebbing of the plasma membrane and carry a diverse cargo that regulate multiple processes.

During #inflammation these are produced by activated endothelial cells and released into the #circulation. TEM image of plasma MVs: (2/8) Image
In this study the authors investigated whether endothelial-derived MVs (EC-MVs) contribute to #vascular dysfunction during inflammation.

The authors used an animal model of #sepsis (CLP) and found that this increased EC-MV production (3/8) Image
Read 8 tweets

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