Discover and read the best of Twitter Threads about #VARIANT

Most recents (24)

Tracking #SARSCoV2 #Lineages - Globally

Top lineages -#20DayTrends (#G20):

XBB.1.5 (16.5%)⬇️
XBB.1.16 (10.5%)⬆️
XBB.1.9.1 (7.3%)
FL.4 (4%)
EG.1 (3.6%)
XBB.1.16.1 (3.4%)
XBB.1.9.2 (3.2%)
XBB.2.3.2 (2.6%)
FL.2 (2.5%)
FU.1 (2.1%)

public.tableau.com/app/profile/ra…
Updated 6/4/23 Image
Granular details #Global #20DayTrends

This analysis includes all designated #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 05/15/2023 (6,574 sequences) Image
In Silico Immune escape and ACE2 receptor binding scores (relative to BA.2)*

Data is intended to prioritize select lineages to generate rapid laboratory experiments to gauge immune escape and ACE2 binding affinity.

[Credits in the legend] *Only Spike RBD mutations considered Image
Read 7 tweets
#VariantDashboard #India - #30DayTrends

Top circulating lineages:

XBB.1.16 (61%)
XBB.2.3* (15%) 👀
XBB.1.16.1 (10%)👀
XBB.1.5 (6%)
XBB.1 (1.8%)
XBB.1.9.1 (1.8%)

*includes several newly designated XBB.2.3.x

Tracker: public.tableau.com/app/profile/ra…

Updated: 04/12/2023 Image
Granular details - #VariantDashboard #India - #30DayTrends

XBB.1.16* (71%) is still the dominant variant group in #India

Note: Data limited to few States that are sequencing and rapidly submitting data Image
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time in #India

XBB.1.16* sequence count: 1,795
XBB.1.6.1 sequence count: 299

Hotspots: #Gujarat, #Maharashtra, #Delhi👀, #Karnataka, #TamilNadu, #Haryana

Note: Recent Epi-Weeks are incomplete

public.tableau.com/app/profile/ra… Image
Read 6 tweets
Glad to see @WHO cares and will continue its #VariantTracking efforts!

These decisions generate a domino-type effect often ending up impacting the funds allocated for robust global surveillance efforts

#VariantTrackers have their task cut out...
Important resources to keep you updated with what's happening in the variant world

1. Cov-Spectrum Collection 24 for effective tracking- cov-spectrum.org/collections/24 (@siamosolocani @Asinickle1 @wolfeagle1989)
2. Nick names for effective communication- whn.global/common-names-f… (@TRyanGregory )
Read 7 tweets
🚨 THREAD #VARIANT🚨

Celui-ci va probablement prendre le podium.

XBB.1.17▶️XBB.1 + S:E180V + S:K478R + S:S486P + ORF1a:L3829F + ORF1b:D1746Y + ORF9b:I5T + ORF9b:N55S

▶️S:486P: Echappement immunitaire +++. L'amène au niveau de XBB.1.5
▶️S:E180V: Non significatif.

#Covid19
▶️S:K478R: CM.4.1, BA.2.38.3. Confère un léger avantage d'échappement immunitaire.
▶️ORF1a:L3829F: Très présent dans les séquences de patients chroniques immunodéprimés, et dans les BQ*. NSP6/ Son effet est inconnu.
▶️ORF1b:D1746Y: Rare.NSP12. Cible

#Covid19 #Variant
de plusieurs antiviraux, dont le remdevisir. Emergeant d'un patient chronique, peut donner un avantage contre des antiviraux. Pure spéculation.
▶️ORF9b:I5T: Présent dans XBB.1.9* et seule mutation pouvant expliquer son apparente avantage sur 1.5*. .

#Covid19 #Variant
Read 5 tweets
De huidige uitbraak van #vogelgriep is zorgelijk.

Er is gelukkig nog geen bewijs voor mogelijke mens-op-mens verspreiding en zeer beperkt bewijs voor verspreiding tussen zoogdieren.

Maar dit is wel hét moment om de #preparedness riemen aan te trekken
hoe groot de kans is op een uitbraak onder mensen, wat de route van het virus zal zijn, hoeveel slachtoffers er kunnen vallen: geen idee ⁉️
Maar volgens Ron Fouchier heeft het virus maar een handvol genetische aanpassingen nodig om #pandemic te worden
@nrc
nrc.nl/nieuws/2023/02…
Het is daarom slim om nu na te gaan: welke lessen uit de #coronapandemie willen we dan meenemen?
We weten dat
- snel handelen in beginfase essentieel is
- er dan nog veel onzekerheid zal zijn
Welke bruikbare #communicatie lessen komen dan van pas?
@JuliavanWeert @DeMarijndebruin
Read 18 tweets
#BoJo branded '#provenliar' as Met Police issue fines over Downing Street parties -2 hrs ago
- #ScotlandYard statement confirming twenty fixed penalty notices will be issued for breaches of Covid-19 rules following lockdown-busting parties in #SesameStreet
ImageImage
#SesameStreet's Awards, The Worst Actor Winner.
The #UK health secretary, #Hancock #CrocodileTears | Dec 09, 2020
- “It’s been such a tough year for so many people and there’s William #Shakespeare putting it simply for everybody...
Read 25 tweets
#santépublique et #prévention
La distorsion entre la mobilisation de la France vantée avant hier dans le cadre de la journée internationale de la préparation aux épidémies et le fait que près de 3 ans après nous ne sommes toujours pas capable d'un minimum d'anticipation face à
1/
une #pandémie dont on s'efforce par ailleurs chaque jour de banaliser les incidences - et avec succès au demeurant puisque des hospitaliers considèrent effectivement qu'on va pouvoir vivre gentiment comme ça et faire avec cette mortalité résiduelle puisque l'état des patients
2/
accueillis en urgence et réa est moins grave que début 2020 (🧞‍♂️merci la vaccination ...) donc que la #banalisation des décès et l'#invisibilisation des personnes invalidées par des séquelles post infectieuses #covidlong passe vraiment crème. Cela d'autant que les gens ont trop
3/
Read 18 tweets
THREAD XBB

XBB.1.5 vient d'obtenir un surnom, Kraken. P̈révalent à New York, il booste une forte vague

Il est récemment apparu en France, en faible nombre, dans 4 régions

Les XBB pouvant causer une de nos prochaines vagues, ils méritent une petite synthèse.

#Covid19 #Variant Image
XBB est un recombinant de BJ.1 (branche BA.2.10), et de BM.1.1.1 (branche BA.2.75.3) avec une cassure en Spike, repéré le 12 septembre. La majeure partie du virus, après la cassure, provient de M.1.1.1.

#Covid19 #Variant Image
XBB se retrouve avec 5 mutations Spike améliorant l'affinité aux recepteurs ACE2 (dont Y144del, la meilleure), et donc l'infectivité du virus, 3 mutations d'échappement immunitaire ++ (346T, 460K, 486S), 3 mutations d'EI + (445P, 446S, 490S), et deux standard.

#Covid19 #Variant
Read 9 tweets
🗓️ vanaf morgen, 11 april 2022, vervalt het algemene advies om voor een #coronatest naar de #GGD te gaan

voor de meeste mensen is een #zelftest voldoende voor testen bij mogelijke COVID19 symptomen

het "zicht op het virus" vervalt daarmee deels

1/

rijksoverheid.nl/onderwerpen/co…
wat blijft:
-Testen bij klachten
-#Isolatie na positieve #COVID19 test
-#Quarantaine na nauw contact (tenzij vaccinatie en aantal andere regels)

#isolatie mag na 5 dagen opgeheven worden, mits 24 uur klachtenvrij, en tot dag 10 voorzichtig zijn 😷

2/

wat verandert:
- wie er nog wél bij de GGD mogen komen testen
- ons #ZichtOpHetVirus 🔎📊

3/
Read 16 tweets
🔊Heads up, at 11am PST we'll look at the new BA.2 #Covid variant, which now accounts for more than 50% of new infections in New York/New England, and almost 35% in California. Join us here @EthnicMediaSvc or via FB fb.me/e/1qjhPsdw7 @LcacNews @StanfordChild
Welcome to today's briefing, "The BA.2 #Variant Gains Ground: Are We Heading Back to the Future?"
You can follow the discussion on Twitter @EthnicMediaSvc or via FB Live fb.me/e/1qjhPsdw7
A question from our moderator @sunita37 on how the BA.2 #variant emerged. "BA.2 is similar to #omicron that shares a common ancestor with #omicron but it is an ancestor that we do not know," says @DrBenNeuman
Read 58 tweets
Nuove varianti e tornano le preoccupazioni, questo thread non vuole essere un riassunto delle varianti attuali ma una GUIDA per districarsi nelle informazioni e per pesarle:

1/n

#Covid_19 #Variant #OmicronXE #Omicron #XE #XD
1) questo virus è il più studiato della storia, abbiamo un livello di dettaglio mai visto prima. Moltissime delle informazioni sono estremamente tecniche e difficili da capire e contestualizzare. I migliori scienziati al mondo sono al lavoro sulle varianti --> don't panic
2/n
2) i virus naturalmente mutano e lo fanno in continuazione: è nella loro 'natura'. Non dobbiamo stupirci o preoccuparci per una nuova variante, fin quando circolerà, muterà.
3/n
Read 7 tweets
Study from @Yale looking at the association between the #Pfizer #COVID19 #vaccine and #SARSCoV2 positivity among 542 adolescents when the Delta variant of SARS-CoV-2 was predominant and within 4 months of the vaccine rollout for adolescents showed:
-estimated effectiveness of the #pfizer vaccine was 91%, with 93% protection against symptomatic infections & 85% effectiveness against asymptomatic infection
Conclusion: These findings suggest that the #Pfizer #vaccine was effective in adolescents within 4 months of #immunization, including against infections caused by the #Delta #variant.

jamanetwork.com/journals/jaman…
Read 4 tweets
(Only in China and) #Canada finds suspected "deer-to-human" new crown case or isolated case | Mar 2
- According to comprehensive foreign media reports, Canadian researchers recently discovered a highly mutated #variant of the new crown in #deer in #Ontario
tellerreport.com/news/2022-03-0…
The novel 'crona virus' #batflu Vs #Catflu - SIMPSON CARTOON | 6.6.2020
- The today novel corona virus that spreading day by day the simmilar virus was documented in simpson cartoon sereis like All other pridictions.
'#Pneumovirus' #PalmBeachCounty Animal Care and Control quarantines dogs following outbreak | Mar 1
- "Because it's #novel and we don't have a #vaccine for it currently, the dogs just don't have good immunity to it," said Dr. Sara Chapman.
wptv.com/lifestyle/pets…
Read 4 tweets
A lot of people around the world are feeling elated & treating emergence of #Omicron as a signal of the end of the pandemic! Most believe it will bring “endemicity".

Does it make sense? 1/
How can anyone think we’ve got this under control when a new #variant suddenly pops up, nearly completely evades immunity & then sweeps the world in a few weeks?
Further, we must know “mutations have no schedule.” Could be 4-6 months, could be next week. 2/
“to what extent will #Omicron-like emergence events characterize "endemic" circulation of #SARS2? Given it occurred once, having it occur again would not be at all surprising,…whether to expect this every year or every ten.” 3/

Read 5 tweets
Latest @WHO #TechnicalBrief on #Omicron
Overall risk remains very high & threat depends on

1⃣Transmissibility of #variant
2⃣How protective vaccines & prior infection are
3⃣Virulence of variant
4⃣Understanding of dynamics & uptake PHSM

Full 🧵👇 (1/)
who.int/publications/m…
Epidemiology (1)
-#Omicron has large growth advantage over #Delta - grows significantly more than Delta in countries with community transmission
- Evidence that immune evasion contributes to rapid spread
-Wk 52, global weekly #COVID19 incidence ⬆️ 71% compared to prior wk
(2/)
Epidemiology (2)
-Study from HK found #Omicron infects human bronchus tissue faster and better than #Delta
-#UK study found Omicron outcompetes Delta in experiments using cells derived from human nose, but not seen in lung derived cells
-Growth advantage in upper resp tract
(3/)
Read 17 tweets
OK #Covid_19 #COVID19 #Covid #uspoli #canpoli #ukpolitics #EU #worldpoli are you or one of your family members one of the 1/100 predicted to get severely ill from #Omicron the #COVID19 #Covid_19 #Variant despite being 3-4X vaccinated and following public health advice?
A THREAD:
And so it seems world leaders around the globe have finally come together - to declare that 1/100 people with #Omicron experiencing severe disease and/or death is an acceptable number for "a productive economy" - what does that mean if YOU or an at-risk family member is 1/100?
First you must accept the cold hard fact that nobody any longer gives a single solitary flying shit that you or your family member(s) are now after 2 years of "we're all in this together" staring down the very short barrel of a rapidly increased mortality risk from #Omicron.
Read 26 tweets
Government leaders have failed to put the health, well-being & dignity of every resident at the center of our #COVID19 response. Many of us are suffering unnecessarily and every sector is impacted by preventable challenges. 🧵 1/

boston.cbslocal.com/2021/12/22/cov…
This all could have been avoided. Our government leaders could have prioritized the needs of residents rather than protecting special interests and getting lulled into believing that a privatized response would save us. 2/ #mapoli #bospoli
We know how stressed our community members feel, how our nurses & doctors are #burntout, how much our teachers & students want to safely return to the classroom & how worried our parents are for their children and their aging parents, never mind themselves. 3/

@MTA @AFTMass
Read 23 tweets
Interessant, és del meus temes "preferits", tenint en compte al q em dedico. Infecció laboratorial de #SARSCoV2. Ho té tot, exper. animal, mossegada animal infectat, treball amb diverses #variants, contaminació ambiental. Un must, i dona per discussió. taiwannews.com.tw/en/news/437285…
#SARSCoV2 Moltes lectures i lliçons en aquest article. Primera; els accidents, les infeccions laboratorials existeixen i un treballador pot potencialment treure el virus a exterior i infectar a la comunitat (per això mai es pot descartar #labaccident). Segona, els incidents...
s'han d'investigar; de fet, la persona infectada..."was bitten for a second time in November by a mouse infected with the Alpha strain". No era 1er accident i això no diu massa de la persona ni del centre. Tercer, els laboratoris que treballen amb #SARSCoV2 poden experimentar...
Read 9 tweets
1/You have no doubt heard much lately about the recently designated #COVID19 #variant, #omicron.

I would like to distill what we know, what we do not know, and what this all means for you right now.
2/On 11/26/21, the @WHO officially designated B.1.1.529 (#omicron) a "variant of concern."

It cited a "large number of mutations, some of which are concerning" and "preliminary evidence" of "an increased risk of reinfection with this variant.."

who.int/news/item/26-1…
3/In short, scientists are concerned because #omicron exhibits an unusual number of mutations across the #SARSCoV2 genome, with >30 on the spike protein.

The spike is the part of the virus that allows it to gain access to human cells and reproduce. (h/t @_nference)
Read 20 tweets
📌 CE SOIR dans #RuthElkrief2022

🗣️ @ruthelkrief reçoit le professeur Alain Fischer (@PrAlainFischer) : "Monsieur #Vaccin" vous répond

📺 À suivre à partir de 20h30 sur #La26 Image
🔴🗣️ #VariantOmicron - "Il est absolument légitime de prendre des précautions [mais] il ne faut pas paniquer, il faut écouter les mots strictement dans le sens qu'ils ont et considérer qu'il y a un risque" : @PrAlainFischer dans #RuthElkrief2022 | @ruthelkrief.
🔴🗣️ #VariantOmicron - "Il y a des signaux disant que ce #variant est potentiellement dangereux. Mais cela ne veut pas dire qu'il va prendre le dessus sur le variant actuel", #Delta, "déjà très transmissible" : @PrAlainFischer dans #RuthElkrief2022 | @ruthelkrief.
Read 11 tweets
Dans #Spike #Variant #Omicron je découvre une RUPTURE qui ne suit plus adaptation virus à hôte.
SOUPÇONS DE MANIPULATION DE LABORATOIRE!
images & GLOBAL "STRATEGY" FOR MUTATIONS AND EVOLUTION OF VARIANTS OF THE SARS-COV2 GENOME?
DOI: 10.29121/granthaalayah.v9.i6.2021.4039 ImageImageImageImage
Observez la région bleue dans mes images dès spikes variants (Fibonacci UA/CG de 2584 bases). Elles sont à ZERO dans #Omicron
@ArnoutDomitille Observez la région bleue dans mes images dès spikes variants (Fibonacci UA/CG de 2584 bases). Elles sont à ZERO dans #Omicron
Read 4 tweets
B.1.1.529 seems to have gone from 0.1% to 50% in just a couple of weeks, when it took Delta several months to achieve that..!!

Brace up folks..!!
#NuVariant

Things are getting worrisome folks..!! Read and understand this thread..!!
Read 12 tweets

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