Discover and read the best of Twitter Threads about #génomes

Most recents (12)

Excited to share our new manuscript on a novel #neuropeptide family that regulates #feeding across #evolution. Kudos to @Pat_TFrancisco for tackling this challenging project and coming up with the name @marmite . #homeostasis biorxiv.org/content/10.110… 1/22
Also kudos to all our collaborators @TastekinIbrahim @EzraGili @fern1_ana @BartDeplancke @albinojorgemai @alisson_gontijo which allowed us to expand the scope of our study and contributed critical insights. It takes a village 2/22
The sequencing of #genomes has been a major milestone in #biology. We have precise maps of the #genome of animals and we think that we know all the major players. Especially the conserved ones which are so important that most animals have them. But is it really like that? 3/22
Read 22 tweets
This is a thread about how anyone can use publicly accessible sequence databases and free software to discover new things about #genomes, #biology, and life on earth.

#Bioinformatics #Genomics #Evolution #Science #MolecularBiology #DNA #Research #DataScience #LifeSciences Image
Genomes are absolutely loaded with complex information, most of which we still don’t understand.

Complete and near complete genome sequences are now available for many organisms.

However, decoding the information in these genomes remains a slow and difficult process. Image
A large proportion of most published genome sequences consist of DNA that is incompletely understood in terms of its evolutionary origins and functional significance. Image
Read 21 tweets
Our paper ‘Current applications and future promise of genetic/genomic data for conservation in an Aotearoa New Zealand context’ is now available as an open-access peer-reviewed report in @docgovtnz’s Science for Conservation series: doc.govt.nz/globalassets/d… 🧵1/7
To support conservation practitioners in identifying appropriate tools to inform conservation management, we review opportunities, challenges and costs associated with available & emerging tools, incl #pedigrees, #microsatellites, #genomes, #eDNA, #aDNA, #pangenomes & more! 2/7
This is a dynamic field, & costs (incl 💰🕒🥼🖥️) are rapidly changing. With >300 references, we hope this paper will be a useful resource for #conservation researchers & practitioners keen to apply the #conservation toolbox, esp. in an Aotearoa context. 3/7 A diagram describing conser...
Read 7 tweets
Sur les cas de #variole #simesque (#MPXV) détectés de par le monde, quelques réflexions d'épidémiologie, de modélisation et d'évolution de l'équipe.

Car, pour le moment, ce sont surtout les #génomes viraux qui apportent des indications !

ecdc.europa.eu/en/news-events…

1/N
Sans entrer dans les détails, ces infections sont causées par un (gros) #virus à #ADN.

Pour des détails cliniques et thérapeutiques, @MarcGozlan a un post très détaillé en #acceslibre 👇
lemonde.fr/blog/realitesb…

2/N
Les épidémies de #MPXV sont beaucoup étudiées par les modélisateurs car elles ont, habituellement, un #R0<1. Autrement dit, on s'attend à ce qu'elles régressent vite.

Notre collègue @jlloydsmith les a beaucoup analysées :
journals.plos.org/ploscompbiol/a…
3/N
Read 14 tweets
"We're talking about [] redesigning organisms... not just edit #genomes but also [], write a new code for life. We'll have write-level permissions. We already started to see some of that this year. #COVID19 #vaccines, they make use of engineered code in the form of #mRNA."
Apr 2021, #WEF: "The new technologies driving the #4IR will be key to the global recovery... but only if they are harnessed properly."

"Synthetic #biology includes #CRISPR, the gene-editing technology currently being used to fight #COVID19."

#mRNA

weforum.org/agenda/2021/04… Image
2019: "More than a technological change, this #biodigital convergence may transform the way we understand ourselves & cause us to redefine what we consider #human or natural."

#4IR #Disruption #Canada



horizons.gc.ca/en/2020/02/11/… ImageImageImage
Read 3 tweets
We are delighted to announce the release of #PhageAI 0.10.0: extended repository and the new #phage #prediction tool: #chronic #lifecycle. 1/4
Each of the #phage genome has computed a new numerical vector representation by #Phage2Vec technology, re-classified #lifecycles and re-computed nearest neighborhood what introduced updated alignment-free top-10 similar #bacteriophages registry. 2/4
Furthermore, we released beta #bacteriophage #taxonomy #prediction tool.

Feel free to extend your account role from basic to Expert user using "My Profile" view, to access it from the @PhageAI. 3/4
Read 4 tweets
Daily Bookmarks to GAVNet 01/08/2021 greeneracresvaluenetwork.wordpress.com/2021/01/08/dai…
Along with vaccine rollouts, the U.S. needs a National Hi-Fi Mask Initiative

statnews.com/2021/01/07/nat…

#PandemicResponse #vaccines #masks #COVID19
Read 10 tweets
There are reports coming out in the Danish media of novel mutations emerging in #SARSCoV2 in #mink tinyurl.com/y5gbwype

SARS-CoV-2 can infect multiple mammalian carnivores and has now been detected in multiple mink farms to date 👇
Across high coverage #SARSCoV2 genomes isolated from mink @GISAID we pick up unique mutations including one in the #spike protein which has appeared at least five times in phylogenetically distant #mink lineages. Image
This mutation, falling within the receptor binding domain, may be a good candidate for adaptation of #SARSCoV2 to #mink hosts. While this mutation has been seen in #SARSCov2 in human circulation it is rare. Currently available mink genomes fall in the diversity of human #SARSCoV2
Read 4 tweets
📢🎉The work of #Bat1K is featured on the cover in the latest issue of @nature: “Six reference-quality #genomes reveal evolution of #bat adaptations” 🦇🧬 #bats Our thread 👇 on the paper:nature.com/articles/s4158… 📸: Olivier Farcy(1/n) Image
📢Have you ever wondered how 🦇 manage to do what they do? #bats have extraordinary adaptations, including powered #flight, laryngeal #echolocation, #vocal #learning and an exceptional #longevity with unique #immunity and resistance to #cancer! 📸: @DanielWhitby5 (2/n) Image
A #Bat1K team led by @Sonja_Vernes @EmmaTeeling1 @hillermich @TheGeneMyers has just published the raw genetic material that codes for these unique 🦇 adaptations and #superpowers in @nature! #bats #genomics #cool! (3/n) Image
Read 32 tweets
Dear #Bat1K community! Facing the current situation we have something to share with you. Please keep on reading this thread on #bats and #COVIDー19 🦇👇 1/n
We all find ourselves in the midst of a #global #pandemic. Our life is changing and we all have to adapt. Meanwhile, we get to hear the news, densely packed with the #coronavirus, the disease it causes, and also: #bats. 2/n
#Researchers around the globe are doing their best to quickly understand the virus and its outbreak. Nevertheless, the rush to report and communicate complex scientific results has sometimes led to confusion, mistrust and ultimately even fear and hatred towards #bats 3/n
Read 25 tweets
1/13 While #COVID19 warrants our attention and swift, concerted action, we cannot forget about the existing high global burden diseases like #tuberculosis.
2/13 In ”Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases” preview.tinyurl.com/vyhckyc, @crobinhold1 @Valafarlab & I provide a roadmap for navigating #Illumina coverage bias when #sequencing Mtb #genomes
3/13 We use a #phylogenomic filtering step to remove evolutionary signals isolating systematically low coverage and provide lists of #Illumina #blindspots for seven #sequencing workflows (lib prep + instrument) at single-base resolution
Read 14 tweets

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